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ATG4D 抗体 (AA 227-257)

This anti-ATG4D antibody is a 兔 多克隆 antibody detecting ATG4D in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN1449634
发货至: 中国

Quick Overview for ATG4D 抗体 (AA 227-257) (ABIN1449634)

抗原

See all ATG4D 抗体
ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

适用

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人, 小鼠

宿主

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克隆类型

  • 68
  • 9
多克隆

标记

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This ATG4D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 227-257

    纯化方法

    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS

    免疫原

    KLH conjugated synthetic peptide between 227~257 amino acids from the Center of Human APG4D Genename: ATG4D

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

    别名

    APG4D / ATG4D

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.Synonyms: AUT-like 4 cysteine endopeptidase, AUTL4, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D

    分子量

    52922 Da

    基因ID

    84971

    NCBI登录号

    NP_116274

    途径

    Autophagy
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