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PD-L1 抗体 (Extracellular Domain) (PE)

PD-L1 适用: 人 FACS 宿主: 小鼠 Monoclonal J1050 PE
产品编号 ABIN1449174
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗原表位
    • 29
    • 16
    • 15
    • 13
    • 11
    • 11
    • 9
    • 7
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    • 5
    • 4
    • 3
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 168
    • 106
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    宿主
    • 127
    • 59
    • 15
    • 4
    • 4
    • 1
    小鼠
    克隆类型
    • 108
    • 100
    • 2
    单克隆
    标记
    • 98
    • 14
    • 13
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This PD-L1 antibody is conjugated to PE
    应用范围
    • 138
    • 102
    • 60
    • 40
    • 37
    • 28
    • 17
    • 16
    • 16
    • 15
    • 10
    • 7
    • 5
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human PD-1.
    纯化方法
    Protein A agarose
    免疫原
    Fusion protein of the extracellular domain of human PD-1 and the constant region of human gamma1 heavy chain
    克隆位点
    J1050
    亚型
    IgG1
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.09 % NaN3, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274 / PDL1 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells that are undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    基因ID
    29126
    NCBI登录号
    NP_054862
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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