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FNDC3B 抗体 (AA 921-1020) (Cy5)

FNDC3B 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1417194
发货至: 中国
  • 抗原 See all FNDC3B 抗体
    FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
    抗原表位
    • 14
    • 8
    • 7
    • 4
    • 4
    • 1
    AA 921-1020
    适用
    • 40
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 40
    克隆类型
    • 40
    多克隆
    标记
    • 11
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FNDC3B antibody is conjugated to Cy5
    应用范围
    • 31
    • 22
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FNDC3B
    亚型
    IgG
    Top Product
    Discover our top product FNDC3B Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
    别名
    FNDC3B (FNDC3B 产品)
    别名
    FAD104 antibody, PRO4979 antibody, YVTM2421 antibody, 1600019O04Rik antibody, AW550168 antibody, Fad104 antibody, mKIAA4164 antibody, RGD1311673 antibody, FNDC3B antibody, DKFZp469D136 antibody, fibronectin type III domain containing 3B antibody, FNDC3B antibody, Fndc3b antibody, fndc3b antibody
    背景

    Synonyms: Factor for adipocyte dferentiation 104, FAD104, fibronectin type III domain containing 3B, FLJ23399, HCV NS5A binding protein 37, NS5ABP37, YVTM2421, MGC10002, PRO4979, DKFZp686D14170, DKFZp762K137, FND3B_HUMAN.

    Background: Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.

    基因ID
    64778
    途径
    Positive Regulation of fat Cell Differentiation
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