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- 抗原 See all FNDC3B 抗体
- FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FNDC3B antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Full length fusion protein
- 亚型
- IgG
- Top Product
- Discover our top product FNDC3B Primary Antibody
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anti-Fibronectin Type III Domain Containing 3B (FNDC3B) (AA 5-71) antibody
FNDC3B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibronectin Type III Domain Containing 3B (FNDC3B) (AA 250-299) antibodyFNDC3B 适用: 人, 兔, 犬, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.8 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- FNDC3B (Fibronectin Type III Domain Containing 3B (FNDC3B))
- 别名
- FNDC3B (FNDC3B 产品)
- 别名
- FAD104 antibody, PRO4979 antibody, YVTM2421 antibody, 1600019O04Rik antibody, AW550168 antibody, Fad104 antibody, mKIAA4164 antibody, RGD1311673 antibody, FNDC3B antibody, DKFZp469D136 antibody, fibronectin type III domain containing 3B antibody, FNDC3B antibody, Fndc3b antibody, fndc3b antibody
- 背景
- Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
- UniProt
- Q53EP0
- 途径
- Positive Regulation of fat Cell Differentiation
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