AKR1C3 抗体 (AA 161-270) (Cy7)
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- 抗原 See all AKR1C3 抗体
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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抗原表位
- AA 161-270
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适用
- 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKR1C3 antibody is conjugated to Cy7
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 兔
- 预测反应
- Human,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AKR1C3
- 亚型
- IgG
- Top Product
- Discover our top product AKR1C3 Primary Antibody
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anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibody
AKR1C3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibodyKO Validated AKR1C3 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人 ELISA, FACS, IF 宿主: 兔 Monoclonal 4D12 unconjugated Recombinant Antibody
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibodyVerified AKR1C3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 10-36), (N-Term) antibodyAKR1C3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22754 unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- 别名
- AKR1C3/DD3 (AKR1C3 产品)
- 别名
- AKR1C3 antibody, PGFS antibody, MGC134333 antibody, DD3 antibody, DDX antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, HSD17B5 antibody, hluPGFS antibody, Akr1c18 antibody, aldo-keto reductase family 1, member C3 L homeolog antibody, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1 member C3 antibody, aldo-keto reductase family 1, member C3 antibody, akr1c3.L antibody, AKR1C3 antibody, LOC722496 antibody, Akr1c3 antibody
- 背景
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Synonyms: 17 beta HSD 5, 17 beta hydroxysteroid dehydrogenase type 5, 17-beta-HSD 5, 17-beta-hydroxysteroid dehydrogenase type 5, 2-dihydrobenzene-1, 2-diol dehydrogenase, 3 alpha hydroxysteroid dehydrogenase type II, 3-alpha-HSD type 2, 3-alpha-HSD type II, 3-alpha-HSD type II, brain, 3-alpha-hydroxysteroid dehydrogenase type 2, AK1C3_HUMAN, AKR1 C3, AKR1C3, Aldo keto reductase family 1 member C3, Aldo-keto reductase family 1 member C3, brain, Chlordecone reductase, Chlordecone reductase homolog HAKRb, DD-3, DD3, DDH1, DDX, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase type I, Dihydrodiol dehydrogenase X, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5, Indanol dehydrogenase, KIAA0119, PGFS, Prostaglandin F synthase, Testosterone 17-beta-dehydrogenase 5, Trans-1, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Type IIb 3 alpha hydroxysteroid dehydrogenase.
Background: DD3 is a unique enzyme that can specifically catalyze the dehydrogenation of trans-benzenedihydrodiol and trans-naphthalenedihydrodiol.,Human liver contains isoforms of dihydrodiol dehydrogenase (DD1, DD2, DD3 and DD4), which belong to the aldo-oxo reductase/aldo-keto reductase (AKR) superfamily, have 20Alpha- or 3Alpha-hydroxysteroid dehydrogenase (HSD) activity. DD1 is also designated AKR1C1, DDH or DDH1 while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3Alpha-HSD are alternate designations for DD3, while DD4 also can be called AKR1C4, CD or CHDR. DD1 and DD2 are 20Alpha-HSDs, whereas DD3 and DD4 are the 3Alpha-HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20Alpha-HSD catalyzes the reaction of progesterone to the inactive form 20Alpha-hydroxyprogesterone. The 3Alpha-HSD is a cytosolic, monomeric, NADPH-dependent oxidoreductase that reduces 3-keto-5-dihydrosteroids to their tetrahydro products. DD1 and DD2 are ubiquitously expressed, whereas DD4 mRNA is restricted to the liver.
- 基因ID
- 8644
- 途径
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
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