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OLIG2 抗体 (AA 81-180) (Cy5.5)

OLIG2 适用: 人, 大鼠 FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN1407725
发货至: 中国
  • 抗原 See all OLIG2 抗体
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    抗原表位
    • 15
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-180
    适用
    • 63
    • 42
    • 41
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠
    宿主
    • 70
    • 11
    • 1
    克隆类型
    • 62
    • 20
    多克隆
    标记
    • 44
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This OLIG2 antibody is conjugated to Cy5.5
    应用范围
    • 50
    • 38
    • 21
    • 13
    • 12
    • 12
    • 12
    • 10
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 大鼠
    预测反应
    Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human OLIG2
    亚型
    IgG
    Top Product
    Discover our top product OLIG2 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    别名
    OLIG2 (OLIG2 产品)
    别名
    olig3.2 antibody, MGC89336 antibody, OLIG2 antibody, BHLHB1 antibody, OLIGO2 antibody, PRKCBP2 antibody, RACK17 antibody, bHLHe19 antibody, wu:fc64g09 antibody, AI604895 antibody, Bhlhb1 antibody, Olg-2 antibody, Oligo2 antibody, RK17 antibody, oligodendrocyte transcription factor 4 antibody, oligodendrocyte transcription factor 2 antibody, oligodendrocyte lineage transcription factor 2 antibody, olig4 antibody, OLIG2 antibody, Olig2 antibody, olig2 antibody
    背景

    Synonyms: Basic domain helix loop helix protein class B 1, Basic helix loop helix protein class B 1, bHLHB1, bHLHe19, Class B basic helix loop helix protein 1, Class B basic helix-loop-helix protein 1, class E basic helix loop helix protein 19, Class E basic helix-loop-helix protein 19, Human protein kinase C binding protein RACK17, Olig2, OLIG2_HUMAN, Oligo2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specic bHLH transcription factor 2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C binding protein 2, Protein kinase C binding protein RACK17, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17.

    Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.

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