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OLIG2 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-OLIG2 antibody is suitable to detect OLIG2 in samples from 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, 犬 和 马. It has been validated for WB 和 IHC.
产品编号 ABIN2777314
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for OLIG2 抗体 (N-Term) (ABIN2777314)

抗原

See all OLIG2 抗体
OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

适用

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人, 小鼠, 大鼠, 斑马鱼, 豚鼠, 犬, 马

宿主

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兔

克隆类型

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多克隆

标记

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This OLIG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    N-Term

    原理

    OLIG2 Antibody - N-terminal region

    序列

    MDSDASLVSS RPSSPEPDDL FLPARSKGSS GSAFTGGTVS SSTPSDCPPE

    预测反应

    Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

    产品特性

    This is a rabbit polyclonal antibody against OLIG2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human OLIG2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31464-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Mitkus, Hyde, Vakkalanka, Kolachana, Weinberger, Kleinman, Lipska: "Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia." in: Schizophrenia research, Vol. 98, Issue 1-3, pp. 129-38, (2007) (PubMed).

  • 抗原

    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

    别名

    OLIG2

    背景

    Background Information: OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14,21)(q11.2,q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Oligodendrocyte lineage transcription factor 2

    Alternative Symbols: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19

    Protein Name: Oligodendrocyte transcription factor 2

    分子量

    32kDa

    基因ID

    10215

    NCBI登录号

    NP_005797

    UniProt

    Q13516
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