BRMS1 抗体 (AA 151-246) (Alexa Fluor 488)
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- 抗原 See all BRMS1 抗体
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
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抗原表位
- AA 151-246
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRMS1 antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BRMS1
- 亚型
- IgG
- Top Product
- Discover our top product BRMS1 Primary Antibody
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anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibody
BRMS1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2D4-2G11 unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) antibodyBRMS1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 90-210) antibodyBRMS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (N-Term) antibodyBRMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) antibodyBRMS1 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 48-77), (N-Term) antibodyBRMS1 适用: 人 WB 宿主: 兔 Polyclonal RB40250 unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (C-Term) antibodyBRMS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibodyBRMS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 1-246) antibodyBRMS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Breast Cancer Metastasis Suppressor 1 (BRMS1) (AA 21-70) antibodyBRMS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))
- 别名
- BRMS1 (BRMS1 产品)
- 别名
- MGC98869 antibody, BRMS1 antibody, BRMS1L antibody, AV003220 antibody, AW554636 antibody, si:zc188c22.3 antibody, si:zc194c5.2 antibody, wu:fb57b08 antibody, zgc:56414 antibody, breast cancer metastasis suppressor 1 antibody, breast cancer metastasis-suppressor 1 antibody, breast cancer metastasis suppressor 1 L homeolog antibody, BRMS1 antibody, Brms1 antibody, brms1.L antibody, brms1 antibody
- 背景
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Synonyms: Breast cancer metastasis suppressor 1, Breast cancer metastasis-suppressor 1, BRMS-1, BRMS1_HUMAN, DKFZp564A063, MGC95128, AV003220, AW554636.
Background: Breast cancer metastasis-suppressor 1 (BRMS1) is 246 amino acid protein that acts as a mediator of metastasis suppression in several types of cancer including ovarian, lung, bladder, and murine mammary. BRMS1 mRNA is expressed in various tissues, including ovary, prostate, testis, and colon, but the protein is primarily detected in term placenta. BRMS1 suppresses metastasis without inhibiting tumorigenicity by modifying several metastasis-associated phenotypes. BRMS1 may participate in transcriptional regulation by binding to the mSin3/histone deacetylase complex. The expression of BRMS1 in certain cells increases connexin Cx43 expression and reduces connexin Cx32 expression. This produces a gap junction that increases intercellular communication, similar to those found in normal breast tissue. BRMS1 is stabilized by Hsp90 and may inhibit NF-_B activity.
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