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SLC25A12 抗体 (AA 101-200) (Alexa Fluor 350)

Slc25a12 适用: 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1394289
发货至: 中国
  • 抗原 See all SLC25A12 (Slc25a12) 抗体
    SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
    抗原表位
    • 14
    • 14
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 36
    • 28
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 50
    克隆类型
    • 50
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This SLC25A12 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 38
    • 23
    • 20
    • 12
    • 12
    • 7
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLC25A12/ARALAR
    亚型
    IgG
    Top Product
    Discover our top product Slc25a12 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
    别名
    SLC25A12/ARALAR (Slc25a12 产品)
    别名
    cb929 antibody, cb1094 antibody, zgc:66248 antibody, wu:fj94c07 antibody, AGC1 antibody, ARALAR antibody, Aralar1 antibody, RGD1561141 antibody, ARALAR1 antibody, 2610002D09Rik antibody, AI839531 antibody, B230107K20Rik antibody, BB129864 antibody, solute carrier family 25 (aspartate/glutamate carrier), member 12 antibody, solute carrier family 25 member 12 antibody, solute carrier family 25 member 12 L homeolog antibody, solute carrier family 25 (mitochondrial carrier, Aralar), member 12 antibody, slc25a12 antibody, SLC25A12 antibody, slc25a12.L antibody, Slc25a12 antibody
    背景

    Synonyms: AGC1, Araceli hiperlarga, ARALAR, ARALAR1, Calcium binding mitochondrial carrier superfamily member, Calcium-binding mitochondrial carrier protein Aralar1, CMC1_HUMAN, Mitochondrial aspartate glutamate carrier 1, SLC25A12, Solute carrier family 25 member 12, solute carrier family 25, member 12.

    Background: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.

    途径
    Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport
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