SLC25A12 抗体 (AA 101-200)
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- 抗原 See all SLC25A12 (Slc25a12) 抗体
- SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
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抗原表位
- AA 101-200
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC25A12 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SLC25A12/ARALAR
- 亚型
- IgG
- Top Product
- Discover our top product Slc25a12 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SLC25A12 (Slc25a12) (Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12 (Slc25a12))
- 别名
- SLC25A12/ARALAR (Slc25a12 产品)
- 别名
- cb929 antibody, cb1094 antibody, zgc:66248 antibody, wu:fj94c07 antibody, AGC1 antibody, ARALAR antibody, Aralar1 antibody, RGD1561141 antibody, ARALAR1 antibody, 2610002D09Rik antibody, AI839531 antibody, B230107K20Rik antibody, BB129864 antibody, solute carrier family 25 (aspartate/glutamate carrier), member 12 antibody, solute carrier family 25 member 12 antibody, solute carrier family 25 member 12 L homeolog antibody, solute carrier family 25 (mitochondrial carrier, Aralar), member 12 antibody, slc25a12 antibody, SLC25A12 antibody, slc25a12.L antibody, Slc25a12 antibody
- 背景
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Synonyms: AGC1, Araceli hiperlarga, ARALAR, ARALAR1, Calcium binding mitochondrial carrier superfamily member, Calcium-binding mitochondrial carrier protein Aralar1, CMC1_HUMAN, Mitochondrial aspartate glutamate carrier 1, SLC25A12, Solute carrier family 25 member 12, solute carrier family 25, member 12.
Background: Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.
- 途径
- Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport
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