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Ensa 抗体 (AA 51-121) (Alexa Fluor 350)

ENSA 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1393353
发货至: 中国
  • 抗原 See all Ensa (ENSA) 抗体
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    抗原表位
    • 14
    • 14
    • 7
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    AA 51-121
    适用
    • 45
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 2
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 15
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ensa antibody is conjugated to Alexa Fluor 350
    应用范围
    • 34
    • 21
    • 14
    • 12
    • 12
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ENSA/ARPP-19
    亚型
    IgG
    Top Product
    Discover our top product ENSA Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    别名
    ENSA/ARPP-19 (ENSA 产品)
    别名
    ARPP-19e antibody, 1700020C18Rik antibody, 2610007F17Rik antibody, AI451924 antibody, ensa antibody, si:dkeyp-24a7.3 antibody, ensaa antibody, endosulfine alpha antibody, endosulfine alpha a antibody, endosulfine alpha S homeolog antibody, ENSA antibody, Ensa antibody, ensa antibody, ensaa antibody, ensa.S antibody
    背景

    Synonyms: Alpha endosulfine, ARPP 19e, Endosulfine alpha, ENSA_HUMAN.

    Background: Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus. ENSA/ARPP-19, also known as ARPP-19e, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family. ENSA/ARPP-19 is an endogenous regulator of the _-cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic _ cells. It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients. Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms. ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21.3.

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