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Ensa 抗体

KO Validated ENSA 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855066
发货至: 中国
  • 抗原 See all Ensa (ENSA) 抗体
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    适用
    • 45
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 2
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 14
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ensa antibody is un-conjugated
    应用范围
    • 34
    • 21
    • 14
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to ENSA (endosulfine alpha)
    ENSA antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ENSA. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Ensa (ENSA) (Endosulfine alpha (ENSA))
    别名
    endosulfine alpha (ENSA 产品)
    别名
    ARPP-19e antibody, 1700020C18Rik antibody, 2610007F17Rik antibody, AI451924 antibody, ensa antibody, si:dkeyp-24a7.3 antibody, ensaa antibody, endosulfine alpha antibody, endosulfine alpha a antibody, endosulfine alpha S homeolog antibody, ENSA antibody, Ensa antibody, ensa antibody, ensaa antibody, ensa.S antibody
    背景
    The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Cellular Localization: Cytoplasm
    分子量
    13 kDa
    基因ID
    2029
    UniProt
    O43768
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