GLIS2 抗体 (AA 271-350) (Alexa Fluor 647)
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- 抗原 See all GLIS2 抗体
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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抗原表位
- AA 271-350
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适用
- 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLIS2 antibody is conjugated to Alexa Fluor 647
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GLIS2
- 亚型
- IgG
- Top Product
- Discover our top product GLIS2 Primary Antibody
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anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 332-505) antibody
GLIS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (N-Term) antibodyGLIS2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 183-232) antibodyGLIS2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-GLIS Family Zinc Finger 2 (GLIS2) (AA 83-132) antibodyGLIS2 适用: 人, 大鼠, 小鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
- 别名
- GLIS2 (GLIS2 产品)
- 别名
- glis2b antibody, nkl-A antibody, xNKLb antibody, NKL antibody, NPHP7 antibody, Gli5 antibody, Klf16 antibody, Nkl antibody, glis2a antibody, nphp7 antibody, GLIS family zinc finger 2 L homeolog antibody, GLIS family zinc finger 2 antibody, GLIS family zinc finger 2 S homeolog antibody, glis2.L antibody, GLIS2 antibody, Glis2 antibody, glis2.S antibody
- 背景
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Synonyms: NPHP7, NKL, GLI kruppel family member 2, GLI similar 2, GLI-similar 2, GLIS 2, GLIS family zinc finger 2, glis2, GLIS2_HUMAN, Kruppel like zinc finger protein GLIS2, Neuronal Krueppel-like protein, Tax helper protein, THP, Zinc finger protein GLI2, Zinc finger protein GLIS2.
Background: GLIS2 is a 524 amino acid protein that belongs to the GLI C2H2-type zinc-finger protein family. By recruiting the corepressors CtBP1 and HDAC3, GLIS2 represses the transcriptional activation mediated by a??-catenin in the Wnt pathway. GLIS2 can act either as a transcription repressor or as a transcription activator and may be involved in neuron differentiation. Mutations of GLIS2 may be associated with development of progressive chronic kidney disease with characteristics resembling nephronophthisis. GLIS2 contains five tandem Cys(2)-His(2) zinc finger motifs that exhibit the highest homology to those of members of the GLI and Zic subfamilies of Kr??ppel-like proteins. GLIS2 is expressed at high levels in kidney and at low levels in heart, lung and placenta.
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