GLIS2 产品
(GLIS Family Zinc Finger 2 (GLIS2))
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This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010].
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Featured GLIS2 Categories
Recommended GLIS2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7176582
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (2)
Cat. No.
ABIN2779249
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6735915
Quantity
100 μL
Datasheet
Datasheet
Recommended GLIS2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (2)
Cat. No.
ABIN3092777
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355212
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3136720
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GLIS2 Products
: "Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis." in: Nature genetics, Vol. 39, Issue 8, pp. 1018-24, (2007) (PubMed).Synonyms and alternative names related to GLIS2
GLIS family zinc finger 2 L homeolog (glis2.L), GLIS family zinc finger 2 (GLIS2), GLIS family zinc finger 2 (Glis2), GLIS family zinc finger 2 S homeolog (glis2.S), Gli5, glis2a, glis2b, Klf16, NKL, Nkl, nkl-A, NPHP7, nphp7, xNKLbProtein level used designations for GLIS2
- Kruppel-like zinc finger protein GLIS2
- Gli-Kruppel zinc-finger protein NKL
- GLI-similar 2
- GLI-similar protein 2
- nephrocystin-7
- neuronal Krueppel-like protein
- zinc finger protein GLIS2
- GLI-Kruppel family member GLI5
- Kruppel-like factor 16 (neuronal)
- zinc finger protein GLI5
- GLIS family zinc finger 2
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