TRPM7 抗体 (AA 800-850)
-
- 抗原 See all TRPM7 抗体
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
-
抗原表位
- AA 800-850
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TRPM7 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TRPM7
- 亚型
- IgG
- Top Product
- Discover our top product TRPM7 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
- 别名
- TRPM7 (TRPM7 产品)
- 别名
- cb495 antibody, TRPM7 antibody, chak antibody, chak1 antibody, ltrpc7 antibody, trp-plik antibody, ALSPDC antibody, CHAK antibody, CHAK1 antibody, LTRPC7 antibody, TRP-PLIK antibody, 2310022G15Rik antibody, 4833414K03Rik antibody, 5033407O22Rik antibody, LTrpC-7 antibody, Ltpr7 antibody, Ltrpc7 antibody, TRPPLIK antibody, Chak antibody, Trp-plik antibody, transient receptor potential cation channel subfamily M member 7 antibody, transient receptor potential cation channel, subfamily M, member 7 antibody, TRPM7 antibody, trpm7 antibody, Trpm7 antibody
- 背景
-
Synonyms: CHAK, CHAK1, ALSPDC, LTRPC7, LTrpC-7, TRP-PLIK, Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, TRPM7
Background: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
- 基因ID
- 54822
- UniProt
- Q96QT4
-