c-MET 抗体
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- 抗原 See all c-MET (MET) 抗体
- c-MET (MET) (Met Proto-Oncogene (MET))
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This c-MET antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 特异性
- Anti-human c-Met
- 产品特性
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding human c-Met
- 克隆位点
- BCI-3E7
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product MET Primary Antibody
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- c-MET (MET) (Met Proto-Oncogene (MET))
- 别名
- c-Met (MET 产品)
- 背景
- C-MET is a receptor tyrosine kinase that is activated upon Hepatocyte Growth Factor (HGF) binding. c-MET is produced as a single-chain precursor and plays en essential role in embryonic development and wound healing. It belongs to the class of Single-pass type I membrane proteins and it is normally expressed by cells of epithelial origin while the expression of HGF is restricted to cells of mesenchymal origin in an almost perfect paracrine paradigm. Overexpression of c-MET can be found in several kinds of tumor progression.
- UniProt
- P08581
- 途径
- RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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