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TNFRSF8 抗体

TNFRSF8 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal mCD30-1 unconjugated
产品编号 ABIN135189
发货至: 中国
  • 抗原 See all TNFRSF8 抗体
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    适用
    • 136
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    小鼠
    宿主
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This TNFRSF8 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD30, Mr 105-120 kDa
    产品特性
    Hamster Anti-Mouse CD30-UNLB
    纯化方法
    Purified
    免疫原
    Mouse CD30-mouse IgG1 fusion protein
    克隆位点
    MCD30-1
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF8 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , Stim - Reported in literature , Costim - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 3 g/106 cells FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vitro functional studies

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Gur-Cohen, Itkin, Chakrabarty, Graf, Kollet, Ludin, Golan, Kalinkovich, Ledergor, Wong, Niemeyer, Porat, Erez, Sagi, Esmon, Ruf, Lapidot: "PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells." in: Nature medicine, Vol. 21, Issue 11, pp. 1307-17, (2016) (PubMed).

  • 抗原
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    别名
    CD30 (TNFRSF8 产品)
    别名
    CD30 antibody, D1S166E antibody, Ki-1 antibody, Cd30 antibody, Ki antibody, TNFRSF8 antibody, TNF receptor superfamily member 8 antibody, tumor necrosis factor receptor superfamily, member 8 antibody, TNFRSF8 antibody, Tnfrsf8 antibody
    背景
    CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. In anti-CD3-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN-γ production. While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.
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