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CD80 抗体

CD80 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal unconjugated
产品编号 ABIN134038
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
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    小鼠
    宿主
    • 87
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    大鼠
    克隆类型
    • 116
    • 77
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    单克隆
    标记
    • 82
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    This CD80 antibody is un-conjugated
    应用范围
    • 113
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    Flow Cytometry (FACS)
    特异性
    Mouse CD80 (B7-1)
    纯化方法
    Purified
    亚型
    IgG2a
    Top Product
    Discover our top product CD80 Primary Antibody
  • 限制
    仅限研究用
  • 浓度
    0.2 mg/ml
    缓冲液
    Purified Ig buffered in PBS, 0.1% NaN and EIA grade BSA to bring total protein concentration to 4-5 mg/ml.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    CD80
    别名
    CD80 (CD80 产品)
    别名
    B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
    背景
    ABIN134038reacts with the murine CD80 (B7-1) molecule. This member of the Ig superfamily, along with CD86 (B7-2), participates in T cell co- stimulation via interactions with CD28 and CTLA-4. CD80 is constitutively ex- pressed on dendritic cells, monocytes, and peritoneal macrophages and it is in- ducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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