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CD11b 抗体 (PE)

ITGAM 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal PE
产品编号 ABIN133957
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
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    小鼠
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    大鼠
    克隆类型
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    单克隆
    标记
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    This CD11b antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD11b (MAC-1, Ly 40)
    纯化方法
    Purified from ascitic fluid via Protein G Chromatography.
    亚型
    IgG2b
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  • 限制
    仅限研究用
  • 浓度
    0.1 mg/ml
    缓冲液
    R-PE conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography)
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b (ITGAM 产品)
    别名
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    背景
    Anti-mouse CD11b (MAC-1) (Ly 40) monoclonal antibody is specific for the 170 kDa subunit of MAC-1, which mediates adhesion to ICAM-1 (CD54) and C3bi. Mac-1 is expressed on granulocytes, macrophages, natural killer cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 is up-regulated on neutrophils after activation. This particular clone blocks cell adherence and C3bi binding but does not block cell medited lysis (1,2,3,4,5,6). Applications include flow cytometry. This clone has been reported to be suitable for use in in vitro and in vivo blocking, immunohistochemistry (acetone-fixed frozen sections (1-20 µg/ml), immunoprecipitation and western blotting.
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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