CD11b 抗体 (Biotin)
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- 抗原 See all CD11b (ITGAM) 抗体
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD11b antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Rat CD11b/c (Macrophages)
- 免疫原
- Rat Peritoneal Macrophages . Fusion Partner: NSO/U mouse myeloma cell line . Immunocyte Donor: BALB/c spleen
- 克隆位点
- OX-42
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGAM Primary Antibody
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- 应用备注
- This clone is reported to work with frozen and paraffin sections (3).
- 限制
- 仅限研究用
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- 浓度
- 0.5 µg/10 cells
- 缓冲液
- Biotin conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography)
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- CD11b/c (ITGAM 产品)
- 别名
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- 背景
- Anti-rat CD11b/c monoclonal antibody recognizes most macrophages including resident peritoneal macrophages, kupffer cells, but only approximately 35% of alveolor macrophages (2). ABIN133346also labels dendritic cells extensively, granulocytes and cells with morphology of microglia in the brain. It precipitates three polypeptides of M.W. 160, 103 and 95 kDa. ABIN133346inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor of iC3b called CR3. anti-rat CD11b/c mAb should prove useful in the recognition of macrophages and microglia. This clone is reported to work with frozen and paraffin sections (3).
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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