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STAT5A 抗体

STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127149
发货至: 中国
  • 抗原 See all STAT5A 抗体
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    适用
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
    • 154
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    多克隆
    标记
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    This STAT5A antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    The antibody recognizes ~95 kDa Stat5.
    纯化方法
    Peptide affinity purified
    免疫原
    Synthetic peptide surrounding amino acid 777 of human Stat5.
    Top Product
    Discover our top product STAT5A Primary Antibody
  • 应用备注
    Western Blot: 2-10 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
    别名
    STAT5 / STAT5A (STAT5A 产品)
    别名
    MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody
    背景
    Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.Synonyms: MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
    基因ID
    6776
    NCBI登录号
    NP_003143
    UniProt
    P42229
    途径
    JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
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