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PRKG1 抗体 (N-Term)

PRKG1 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127130
发货至: 中国
  • 抗原 See all PRKG1 抗体
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    抗原表位
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 42
    • 26
    • 12
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow
    宿主
    • 36
    • 6
    克隆类型
    • 38
    • 4
    多克隆
    标记
    • 24
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKG1 antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 16
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody recognizes 75 kDa and 85 kDa PKG, corresponding to the Molecular Mass of twho PKG isoforms.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide near the N-terminus of Human PKG.
    Top Product
    Discover our top product PRKG1 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 4-8 μg/mL. Immunohistochemistry: 4-8 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.01 % Thimerosal, 30 % Glycerol, 0.5 % BSA
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))
    别名
    CGK1 (PRKG1 产品)
    别名
    prkg1 antibody, zgc:63955 antibody, Pkgi antibody, cGk1 antibody, 1 antibody, PKG antibody, PRKG1B antibody, PRKGR1B antibody, cGK antibody, cGK 1 antibody, cGK1 antibody, cGKI antibody, cGKI-BETA antibody, cGKI-alpha antibody, CGKI antibody, cGKI-beta antibody, AW125416 antibody, Gm19690 antibody, Prkg1b antibody, Prkgr1b antibody, Prkg1beta antibody, protein kinase, cGMP-dependent, type Ia antibody, protein kinase, cGMP-dependent, type I antibody, protein kinase, cGMP-dependent, type 1 antibody, prkg1a antibody, PRKG1 antibody, prkg1 antibody, Prkg1 antibody
    背景
    PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families with similar substrate specificities. Phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility and platelet aggregation. However, recent studies using mice deficient in PKGs have shown that cGMP kinases regulate very specifically distinct pathways which are separate from those used by cyclic AMP kinases.Synonyms: CKG1A, CKG1B, PGK, PKG, PRKG1, PRKGR1A, PRKGR1B, cGKI-alpha, cGMP-dependent protein kinase 1
    基因ID
    5592
    NCBI登录号
    NP_001091982
    UniProt
    Q13976
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