PAK1 抗体
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北京 101111
Quick Overview for PAK1 抗体 (ABIN127054)
抗原
See all PAK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects PAK1
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纯化方法
- Protein A affinity purified
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免疫原
- Recombinant human PAK1
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anti-P21-Activated Kinase 1 (PAK1) (AA 191-280) antibody
PAK1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 4D1 unconjugated
anti-P21-Activated Kinase 1 (PAK1) (Center) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibodyPAK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibodyPAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (pThr423) antibodyPAK1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB11381 unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibodyPAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (AA 245-490) antibodyPAK1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibodyPAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 1 (PAK1) (pThr402) antibodyPAK1 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-2 μg/mL. Immunoprecipitation: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- PAK1 (P21-Activated Kinase 1 (PAK1))
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别名
- PAK1
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背景
- Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFκB activation.Synonyms: Alpha-PAK, PAK 1, PAK alpha, PAK-1, Serine/threonine-protein kinase PAK 1, p21-activated kinase 1, p65-PAK
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基因ID
- 5058
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NCBI登录号
- NP_001122092
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UniProt
- Q13153
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
抗原
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