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Caspase 9 抗体 (Asp330, N-Term)

CASP9 适用: 人 WB, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127028
发货至: 中国
  • 抗原 See all Caspase 9 (CASP9) 抗体
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    抗原表位
    • 24
    • 16
    • 16
    • 16
    • 16
    • 11
    • 5
    • 5
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Asp330, N-Term
    适用
    • 210
    • 129
    • 110
    • 19
    • 17
    • 16
    • 10
    • 1
    • 1
    • 1
    宿主
    • 203
    • 17
    克隆类型
    • 192
    • 28
    多克隆
    标记
    • 120
    • 11
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    This Caspase 9 antibody is un-conjugated
    应用范围
    • 203
    • 81
    • 67
    • 67
    • 61
    • 53
    • 38
    • 38
    • 18
    • 17
    • 16
    • 5
    • 3
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The affinity purified antibody recognizing the active forms of caspase-9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells. The anti-active caspase-9 antibody recognizes only the cleaved caspase-9 (37 kDa). It does not recognize full-length caspase-9 or any other caspases.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide mapping to the N-terminus adjacent to Asp330 of human Caspase-9
    Top Product
    Discover our top product CASP9 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry /Immunocytochemistry: 10-20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS containing 50 % glycerol, 0.5 % BSA, and 0.02 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
  • 抗原
    Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
    别名
    Caspase-9 (CASP9 产品)
    别名
    CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody
    背景
    Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with pro-caspase-9 (47 kDa) and Apaf-1. The complex processes pro-caspase-9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved Caspase-9 further processes other caspases including caspase-3 and caspase-6, to initiate a caspase cascade leading to apoptosis.Synonyms: APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, ICE-LAP6, ICE-like apoptotic protease 6, MCH6
    基因ID
    842
    NCBI登录号
    NP_001220
    UniProt
    P55211
    途径
    MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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