STAT6 抗体 (pTyr641)
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- 抗原 See all STAT6 抗体
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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抗原表位
- pTyr641
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This STAT6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody specifically recognizes activated STAT6 phosphorylated at Tyr641 at 100 kDa. It does not cross-react with non-phosphorylated form of STAT6 nor with unrelated phosphorylation sites.
- 产品特性
- Synonyms: STAT-6, IL-4 Stat, IL-4-STAT, Signal transducer and activator of transcription 6
- 纯化方法
- Size Exclusion Chromatography
- 组件
- incl. positive Control
- 免疫原
- Synthetic phosphopeptide conjuagted to KLH
- 克隆位点
- 1-60E-013
- 亚型
- IgG1
- Top Product
- Discover our top product STAT6 Primary Antibody
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anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 694-801) antibody
STAT6 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 6C10 unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pThr645) antibodySTAT6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 614-663) antibodySTAT6 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 兔, Pig, 马, 豚鼠, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-180) antibodySTAT6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibodySTAT6 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pTyr641) antibodySTAT6 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibodySTAT6 适用: 人, 小鼠 WB, IHC, IHC (p), FACS, IF (cc) 宿主: 兔 Monoclonal 9A7 unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 557-841) antibodySTAT6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-847) antibodySTAT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-847) antibodySTAT6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. ELISA: 0.05 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 1 mL H2O (15 min, RT).
- 缓冲液
- 1 mL2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C/-80 °C
- 储存方法
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Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
- 别名
- STAT6 (STAT6 产品)
- 别名
- D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
- 背景
- The STAT proteins serve as both cytoplasmic signal transducers and nuclear activators of transcription. STATs are mediators involved in cytokine signalling. In response to a specific cytokine signal, STAT proteins are phosphorylated on conserved tyrosine residues. Phosphorylated STAT proteins dimerize via their SH2 domains and move to the nucleus. The STAT dimers bind to specific DNA elements resulting in transcriptional regulation of downstream target genes. STAT6 is activated primarily by IL-4 and IL-13. Upon activation, STAT6 is phosphorylated at tyrosine 641 by Janus Kinase (JAK). Phosphorylated STAT6 forms head-to-tail heterodimers and translocates to the nucleus where it paricipates in transcriptional control.Synonyms: IL-4 Stat, Signal transducer and activator of transcription 6
- 基因ID
- 6778
- UniProt
- P42226
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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