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NR5A1 抗体 (Internal Region)

NR5A1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN122633
发货至: 中国
  • 抗原 See all NR5A1 抗体
    NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
    抗原表位
    • 8
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    Internal Region
    适用
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    宿主
    • 46
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    克隆类型
    • 45
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    多克隆
    标记
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    This NR5A1 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects Steroidogenic factor 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TRIM23 (47 %).
    交叉反应 (详细)
    Species reactivity (tested):Human
    产品特性
    Synonyms: STF-1, SF-1, NR5A1, AD4BP, FTZF1, SF1, Nuclear receptor subfamily 5 group A member 1,Adrenal 4-binding protein, Steroid hormone receptor Ad4BP, Fushi tarazu factor homolog 1
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Synthetic peptide - KLH conjugatedEpitope: internal domain of humanGenename: NR5A1Remarks: The immunizing peptide shows 88 % identity (100 % similarity) with mouse and88 % identity (100 % similarity) with rat.
    Top Product
    Discover our top product NR5A1 Primary Antibody
  • 应用备注
    Immunohistochemistry with formalin fixed paraffin embedded tissues: 2-18 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-80 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1))
    别名
    Steroidogenic Factor 1 (NR5A1 产品)
    别名
    AD4BP antibody, ELP antibody, FTZ1 antibody, FTZF1 antibody, POF7 antibody, SF-1 antibody, SF1 antibody, SPGF8 antibody, SRXY3 antibody, Ad4BP antibody, ELP-3 antibody, Ftz-F1 antibody, Ftzf1 antibody, Ad4BP/SF-1 antibody, Ad4bp antibody, Sf-1 antibody, NR5A1 antibody, sf-1 antibody, elp antibody, sf1 antibody, ftz1 antibody, ad4bp antibody, ftzf1 antibody, SF-1/Ad4BP antibody, SI:zC167P9.2 antibody, ff1d antibody, nr5a2l antibody, nuclear receptor subfamily 5 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1 antibody, nuclear receptor subfamily 5 group A member 1 L homeolog antibody, nuclear receptor subfamily 6 group A member 1 antibody, nuclear receptor subfamily 5, group A, member 1b antibody, NR5A1 antibody, Nr5a1 antibody, nr5a1.L antibody, nr5a1 antibody, NR6A1 antibody, nr5a1b antibody
    背景
    Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.Synonyms: AD4BP, Adrenal 4-binding protein, FTZF1, Fushi tarazu factor homolog 1, NR5A1, Nuclear receptor subfamily 5 group A member 1, SF-1, SF1, STF-1, Steroid hormone receptor Ad4BP
    基因ID
    2516
    UniProt
    Q13285
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Maintenance of Protein Location
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