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CDC7 抗体 (Kinase Domain)

This 兔 多克隆 antibody specifically detects CDC7 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN122614
发货至: 中国
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Quick Overview for CDC7 抗体 (Kinase Domain) (ABIN122614)

抗原

See all CDC7 抗体
CDC7 (Cell Division Cycle 7 (CDC7))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDC7 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Kinase Domain

    特异性

    Reacts with CDC7-Related Protein Kinase (CDC7L1) (family: Protein Kinase, subfamily: CDC7)

    产品特性

    Synonyms: CDC7L1, CDC7-related kinase, HsCdc7, huCdc7, Cell division cycle 7-related protein kinase

    纯化方法

    Peptide immunogen affinity column

    免疫原

    Synthetic peptide - KLH conjugatedEpitope: Kinase domain of humanGenename: CDC7Remarks: The immunizing peptide shows 63 % identity (79 % similarity) with mouse.
  • 应用备注

    Immunohistochemistry on paraffin embedded sections: 5,2 μg/mLntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.7, containing 0.01 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-80 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CDC7 (Cell Division Cycle 7 (CDC7))

    别名

    CDC7

    背景

    CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. CDC7L1 has been documented in a wide range of tissues. One variant is expressed ubiquitously in human tissues while at least one other has been shown to be testis-specific. ESTs have been isolated from several tissue libraries, including normal embryo, gallbladder, lymph node and thymus and cancerous duodenum and embryo.Synonyms: CDC7-related kinase, CDC7L1, Cell division cycle 7-related protein kinase, HsCdc7, huCdc7

    基因ID

    8317

    UniProt

    O00311

    途径

    Mitotic G1-G1/S Phases, DNA Replication
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