Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
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- 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
- Prostaglandin D2 Receptor 2 (PTGDR2)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Reacts with G Protein-Coupled Receptor GPR44 (CRTH2, family: GPCR, subfamily: Prostanoid).
- 纯化方法
- Peptide immunogen affinity column.
- 免疫原
- Synthetic peptide - KLH conjugated
- Top Product
- Discover our top product PTGDR2 Primary Antibody
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anti-Prostaglandin D2 Receptor 2 (PTGDR2) (Extracellular Domain) antibody
PTGDR2 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibody (APC)PTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 APC
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibody (PE)PTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 PE
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (3rd Extracellular Loop), (AA 270-283) antibodyPTGDR2 适用: 小鼠, 大鼠 WB, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (N-Term) antibodyPTGDR2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (Extracellular Domain) antibodyPTGDR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) antibodyPTGDR2 适用: 人 FACS 宿主: 大鼠 Monoclonal BM16 unconjugated
anti-Prostaglandin D2 Receptor 2 (PTGDR2) (AA 329-348) antibodyPTGDR2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 3-6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.01 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-80 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Prostaglandin D2 Receptor 2 (PTGDR2)
- 别名
- CD294 / GPR44 (PTGDR2 产品)
- 别名
- CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
- 背景
- GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells. CRTH2 has been reported to be expressed in the central nervous system, peripheral tissues, and in blood cells, particularly activated T helper-2 cells. Two transcripts have been isolated, a 3.5-kb transcript expressed primarily in the thalamus, frontal cortex, pons, and hippocampus, and a 3.4-kb transcript expressed in fetal liver, leukocytes, and thymus. ESTs have been isolated from B-cell/lung/testis, brain, kidney, liver/spleen, placenta, prostate, testis, and thymus libraries.Synonyms: CRTH2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, DL1R, Putative G-protein coupled receptor 44
- 基因ID
- 11251
- UniProt
- Q9Y5Y4
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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