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CD11b 抗体 (Biotin)

ITGAM 适用: 大鼠 FACS, IHC (fro) 宿主: 小鼠 Monoclonal OX-42 Biotin
产品编号 ABIN120410
发货至: 中国
  • 抗原 See all CD11b (ITGAM) 抗体
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    适用
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    大鼠
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD11b antibody is conjugated to Biotin
    应用范围
    • 260
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Protein G Chromatography
    免疫原
    Rat Peritoneal Macrophages Immunocyte Donor: BALB/c spleen Fusion Partner: NSO/U mouse myeloma cell line
    克隆位点
    OX-42
    亚型
    IgG2a
    Top Product
    Discover our top product ITGAM Primary Antibody
  • 应用备注
    Flow cytometry. Immunohistochemistry on frozen and paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % NaN3 and EIA grade BSA was added as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    别名
    CD11b (ITGAM 产品)
    别名
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    背景
    CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8 % spleen cells, 44 % bone marrow cells and less than 1 % of thymocytes and is commonly used as a microglial marker in nervous tissue.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor
    基因ID
    10116
    UniProt
    Q63001
    途径
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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