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IL2 Receptor beta 抗体

IL2RB 适用: 小鼠 FACS, IP, Func 宿主: 大鼠 Monoclonal TM-BETA1 unconjugated
产品编号 ABIN120200
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 抗体
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    适用
    • 92
    • 77
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    小鼠
    宿主
    • 85
    • 25
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    大鼠
    克隆类型
    • 86
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    单克隆
    标记
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    This IL2 Receptor beta antibody is un-conjugated
    应用范围
    • 73
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    特异性
    This antibody recognises the CD122 cell surface glycoprotein. Clone TM-beta 1 is reported to block IL-2 high affinity binding to the IL-2R beta receptor. We recommend the use of SM2224LE for this purpose.
    纯化方法
    Affinity chromatography on Protein G
    内毒素水平
    Low Endotoxin
    免疫原
    Cells from murine IL-2RB+ transformant TART-mBeta. Lymph node (cells from immunised Sprague Dawley rats were fused with cells of the mouse PA1 myeloma cell line.
    克隆位点
    TM-BETA1
    亚型
    IgG2b
    Top Product
    Discover our top product IL2RB Primary Antibody
  • 应用备注
    Flow Cytometry: 1/10 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C to -70 °C.
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    CD122 / IL2RB (IL2RB 产品)
    别名
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    背景
    CD122 is a 75-85kD molecule also known as interleukin-2 receptor (IL-2R) beta chain. In mouse, CD122 is primarily expressed on natural killer (NK) cells and at lower levels on lymphocyte subsets, monocytes and macrophages. CD122 can associate with the IL-2R alpha chain (CD25) and CD132 to form a functional high affinity receptor complex that binds IL-2. CD132/CD122 heterodimers can also be formed which bind IL-2 with intermediate affinity. IL-2 binding to the IL-2R is important in the generation and differentiation of T lymphocytes and NK cells.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
    基因ID
    16185
    NCBI登录号
    NP_032394
    UniProt
    P16297
    途径
    JAK/STAT Signaling, Growth Factor Binding
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