HLAG 抗体
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北京 101111
Quick Overview for HLAG 抗体 (ABIN119235)
抗原
See all HLAG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacted with denaturated HLA-G heavy chain. The recognized epitope is present only on HLA-G1, -G2 and -G5 Molecules. HLA-G1 and -G2 are membrane bound proteins, HLA-G5 is a soluble protein.
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纯化方法
- Protein A affinity purified immunoglobulin fraction
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纯度
- > 95 % by SDS-PAGE
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免疫原
- Recombinant human HLA-G denaturated heavy chain
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亚型
- IgG1
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应用备注
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Western Blotting (MWs: HLA-G1 approx. 45 kDa, HLA-G2 approx. 45 kDa, HLA-G5 approx. 28 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline pH 7.4 with 15 mM sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
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有效期
- 6 months
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- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
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别名
- HLA Class I alpha G / HLA-G
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背景
- HLA G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of a heavy chain (with a1, a2, a3 domains) and a light chain (beta 2 microglobulin). Alternate splicing provides both soluble and membrane bound forms of HLA G, with two soluble isoforms and four membrane bound isoforms. HLA G may be part of the fetal protection system and is expressed on fetal derived placental cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G
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基因ID
- 3135
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NCBI登录号
- NP_002118
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UniProt
- P17693
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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