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MHC Class II HLA-DP/DQ/DR 抗体 (FITC)

This 小鼠 单克隆 antibody specifically detects MHC Class II HLA-DP/DQ/DR in FACS. It exhibits reactivity toward 人.
产品编号 ABIN118903
发货至: 中国
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Quick Overview for MHC Class II HLA-DP/DQ/DR 抗体 (FITC) (ABIN118903)

抗原

MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

适用

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宿主

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小鼠

克隆类型

  • 38
单克隆

标记

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This MHC Class II HLA-DP/DQ/DR antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

WR18
  • 纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Human HLA Class II. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS.0 myeloma cell line.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilzer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)

    别名

    HLA Class II DP, DR, DQ

    背景

    The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II. The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.Synonyms: DQ, DR, HLA class II histocompatibility antigen DP, MHC class II antigen DP

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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