电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

FCGR1A 抗体

FCGR1A 适用: 人 FACS 宿主: 小鼠 Monoclonal 10-1 unconjugated
产品编号 ABIN1176933
发货至: 中国
  • 抗原 See all FCGR1A 抗体
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    适用
    • 106
    • 25
    • 19
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    宿主
    • 71
    • 40
    • 1
    小鼠
    克隆类型
    • 70
    • 40
    • 2
    单克隆
    标记
    • 40
    • 14
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCGR1A antibody is un-conjugated
    应用范围
    • 78
    • 65
    • 31
    • 25
    • 20
    • 19
    • 12
    • 11
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Human rheumatoid synovial fluid cells and fibronectin-purified monocytes
    克隆位点
    10-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product FCGR1A Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • van Vugt, Heijnen, Capel, Park, Ra, Saito, Verbeek, van de Winkel: "FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo." in: Blood, Vol. 87, Issue 9, pp. 3593-9, (1996) (PubMed).

    Dougherty, Selvendran, Murdoch, Palmer, Hogg: "The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1." in: European journal of immunology, Vol. 17, Issue 10, pp. 1453-9, (1987) (PubMed).

  • 抗原
    FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
    别名
    CD64 (FCGR1A 产品)
    别名
    CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody
    背景
    The 10.1 monoclonal antibody specifically binds to CD64, a 75 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcgammaRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRgamma homodimer to form the functional high affinity FcgammaRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
    Synonyms: FCGR1, FcRI, Fc-gamma RI, IgG Fc Receptor I, High affinity IgG FcR1
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
You are here:
客服