(5 references)-
- 抗原 See all DcR1 (TNFRSF10C) 抗体
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DcR1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 特异性
- Recognizes human TRAIL-R3.
- 交叉反应
- 人
- 交叉反应 （详细）
- Does not cross-react with human TRAIL-R1, -R2 or -R4.
- 纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
- 纯度
- >95 % (SDS-PAGE)
- 免疫原
- Recombinant human TRAIL-R3 (DcR1).
- 克隆位点
- HS301
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF10C Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody
TNFRSF10C 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (APC)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 30-130) antibodyTNFRSF10C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (FITC)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibodyTNFRSF10C 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal TR3-06 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) antibody (PE)TNFRSF10C 适用: 人 FACS 宿主: 小鼠 Monoclonal TRAIL-R3-02 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 51-150) antibodyTNFRSF10C 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C) (AA 25-161) antibodyTNFRSF10C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A1 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 52824-34, (2004) (PubMed).
: "TRAIL regulates normal erythroid maturation through an ERK-dependent pathway." in: Blood, Vol. 103, Issue 2, pp. 517-22, (2004) (PubMed).
: "Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs." in: Cell death and differentiation, Vol. 11 Suppl 1, pp. S86-96, (2004) (PubMed).
: "TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 4, pp. 1814-21, (2003) (PubMed).
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: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
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- 抗原
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- 别名
- TRAIL-R3 (TNFRSF10C 产品)
- 别名
- CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
- 背景
- TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
- UniProt
- O14798
- 途径
- Apoptosis
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