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FLT1 抗体 (Extracellular Domain)

FLT1 适用: 人, 小鼠 WB, IP, IF, EIA 宿主: 小鼠 Monoclonal FLTEWI (EWI) unconjugated
产品编号 ABIN115153
发货至: 中国
  • 抗原 See all FLT1 抗体
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    抗原表位
    • 16
    • 12
    • 11
    • 11
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    Extracellular Domain
    适用
    • 141
    • 66
    • 65
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 140
    • 30
    • 3
    • 1
    小鼠
    克隆类型
    • 142
    • 32
    单克隆
    标记
    • 90
    • 22
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLT1 antibody is un-conjugated
    应用范围
    • 109
    • 48
    • 44
    • 35
    • 22
    • 22
    • 19
    • 14
    • 14
    • 13
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    The monoclonal antibody will recognize recombinant and naturally occurring form of Human VEGFR-1/Flt-1. It cross reacts with Mouse Flt-1 (e.g. natural occurring soluble Mouse Flt-1) in Western blot analysis (Figure 1).
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Protein G Chromatography
    免疫原
    Recombinant Human soluble extracellular Flt-1 protein (D5) (Cat.-No DA3539)
    克隆位点
    FLTEWI (EWI)
    亚型
    IgG1
    Top Product
    Discover our top product FLT1 Primary Antibody
  • 应用备注
    ELISA (1.5-8 μg/mL). Western blotting (1-10 μg/mL). Immunoprecipitation (1-5 μg/mL lysate or reaction volume). Immunofluorescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL
    缓冲液
    PBS
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
    别名
    VEGFR-1 / Flt-1 (FLT1 产品)
    别名
    FLT antibody, FLT-1 antibody, VEGFR-1 antibody, VEGFR1 antibody, FLT1 antibody, flt1b antibody, sFlt1 antibody, AI323757 antibody, Flt-1 antibody, fms related tyrosine kinase 1 antibody, FMS-related tyrosine kinase 1 antibody, vascular endothelial growth factor receptor 1 antibody, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, FMS-like tyrosine kinase 1 antibody, vascular endothelial growth factor receptor-1 antibody, FLT1 antibody, Flt1 antibody, CpipJ_CPIJ012087 antibody, flt1 antibody, FLT-1 antibody
    背景
    VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity. Because sFLT1 has a higher affinity for VEGF than does FLK1, it may function as an inhibitor of VEGF response.Synonyms: FLT, FLT1, FRT, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, VEGF Receptor 1, VEGFR1, Vascular endothelial growth factor receptor 1, Vascular permeability factor receptor
    基因ID
    2321
    NCBI登录号
    NP_001153392
    UniProt
    P17948
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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