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Insulin 抗体

This anti-Insulin antibody is a 小鼠 单克隆 antibody detecting Insulin in IHC (p), IHC (fro) 和 EIA. Suitable for 人, Pig, 小鼠, Cow 和 大鼠.
产品编号 ABIN112214
发货至: 中国

Quick Overview for Insulin 抗体 (ABIN112214)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

适用

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人, Pig, 小鼠, Cow, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

D3E7 (5B6-6)
  • 特异性

    This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.Aff. Const.:6.3 x 108 M-1

    交叉反应 (详细)

    Also reacts to: Proinsulin

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Recombinant Human Insulin.

    亚型

    IgG1
  • 应用备注

    Immunohistochemistry on Frozen Sections. ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Captureantibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Insulin (INS)

    别名

    Insulin

    背景

    Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS

    基因ID

    3630

    NCBI登录号

    NP_000198

    UniProt

    P01308

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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