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XPC 抗体 (C-Term)

XPC 适用: 人 WB, EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1109520
发货至: 中国
  • 抗原 See all XPC 抗体
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    抗原表位
    • 14
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 3
    • 3
    • 1
    宿主
    • 44
    • 5
    克隆类型
    • 45
    • 4
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPC antibody is un-conjugated
    应用范围
    • 34
    • 25
    • 10
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Reacts with Human 105 kDa XPC protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Synthetic peptide derived from C-terminal domain of Human XPC protein
    Top Product
    Discover our top product XPC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
  • 抗原
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    别名
    XPC / XPCC (XPC 产品)
    别名
    RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
    背景
    Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. XPC may play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C (XPC), also known as xeroderma pigmentosum III (XP3). XPC is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.Synonyms: DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125
    基因ID
    7508
    NCBI登录号
    NP_001139241
    途径
    p53 Pathway, DNA Damage Repair
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