XPC 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for XPC 抗体 (C-Term) (ABIN1109520)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- Reacts with Human 105 kDa XPC protein.
-
交叉反应 (详细)
-
Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography on Protein A
-
免疫原
- Synthetic peptide derived from C-terminal domain of Human XPC protein
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
-
-
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
-
别名
- XPC / XPCC
-
背景
- Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. XPC may play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C (XPC), also known as xeroderma pigmentosum III (XP3). XPC is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.Synonyms: DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125
-
基因ID
- 7508
-
NCBI登录号
- NP_001139241
-
途径
- p53 Pathway, DNA Damage Repair
抗原
-