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XPC 抗体 (C-Term)

This anti-XPC antibody is a 兔 多克隆 antibody detecting XPC in WB, EIA 和 IHC (fro). Suitable for 人.
产品编号 ABIN1109520
发货至: 中国

Quick Overview for XPC 抗体 (C-Term) (ABIN1109520)

抗原

See all XPC 抗体
XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

适用

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宿主

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克隆类型

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多克隆

标记

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This XPC antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    C-Term

    特异性

    Reacts with Human 105 kDa XPC protein.

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Synthetic peptide derived from C-terminal domain of Human XPC protein
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
  • 抗原

    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

    别名

    XPC / XPCC

    背景

    Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. XPC may play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C (XPC), also known as xeroderma pigmentosum III (XP3). XPC is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.Synonyms: DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125

    基因ID

    7508

    NCBI登录号

    NP_001139241

    途径

    p53 Pathway, DNA Damage Repair
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