SOCS4 抗体 (C-Term)
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- 抗原 See all SOCS4 抗体
- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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抗原表位
- C-Term
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适用
- 人, Cow, Pig
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This SOCS4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 序列
- C-SKVRVLRIDA PEQQ
- 特异性
- This antibody detects SOCS-4 at C-term.
- 交叉反应 （详细）
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Species reactivity (expected):Pig, Bovine.
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Synthetic peptide with sequence from the C Terminus of Human SOCS4 (NP_543143.1, NP_955453.1). Genename: SOCS4
- Top Product
- Discover our top product SOCS4 Primary Antibody
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anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254) antibody
SOCS4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-270) antibodySOCS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodySOCS4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodySOCS4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254) antibodySOCS4 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31389 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 234-262) antibodySOCS4 适用: 人 WB, IF, IHC (p), EIA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodyVerified SOCS4 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Tris saline, pH ~7.3
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
- 别名
- SOCS4 (SOCS4 产品)
- 别名
- SOCS7 antibody, socs4 antibody, SOCS4 antibody, 3110032M18Rik antibody, A730004F22Rik antibody, AI427843 antibody, AU015727 antibody, AU015859 antibody, Socs7 antibody, SOCS6 antibody, socs7 antibody, socs4a antibody, suppressor of cytokine signaling 4 antibody, SOCS4 antibody, socs4 antibody, Socs4 antibody
- 背景
- Accumulating evidence has demonstrated that cytokine receptor signaling is negatively regulated by a family of Src homology 2 domain-containing adaptor molecules termed SOCS (Suppressor of Cytokine Signaling) (1-3). Currently, there are eight members of the SOCS family that have been recognized, SOCS-1, -2, -3, -4, - 5, -6, -7 and CIS. Structurally, the SOCS proteins are composed of an N-terminus region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C-terminus motif that has been called the SOCS box (4). The SOCS proteins appear to form part of a classical negative feed back loop that regulates cytokine signal transduction via a STATinduced transcriptional mechanism (5). Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. Within the SOCS subfamily, SOCS-4, SOCS-5, SOCS-6, SOCS-7 remain poorly understood (6). On the basis of structural considerations, it would be expected that SOCS-4, -5, -6, and -7, like SOCS-1, SOCS-2, SOCS-3 and CIS, act to negatively regulate signal transduction (4), but it is uncertain which specific cytokine is involved (7-9).Synonyms: SOCS-4, SOCS-7, SOCS7, Suppressor of cytokine signaling 4, Suppressor of cytokine signaling 7
- 基因ID
- 122809
- NCBI登录号
- NP_543143
- UniProt
- Q8WXH5
- 途径
- JAK/STAT Signaling, EGFR Signaling Pathway
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