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SOCS4 抗体 (AA 227-254)

SOCS4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029046
发货至: 中国
  • 抗原 See all SOCS4 抗体
    SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
    抗原表位
    • 13
    • 12
    • 9
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 227-254
    适用
    • 46
    • 4
    • 2
    • 1
    宿主
    • 41
    • 4
    • 1
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 26
    • 4
    • 4
    • 4
    • 4
    • 4
    This SOCS4 antibody is un-conjugated
    应用范围
    • 44
    • 33
    • 17
    • 16
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Antigen affinity purified
    免疫原
    A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
    亚型
    Ig Fraction
  • 应用备注
    Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the SOCS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
    别名
    SOCS4 (SOCS4 产品)
    别名
    SOCS7 antibody, socs4 antibody, SOCS4 antibody, 3110032M18Rik antibody, A730004F22Rik antibody, AI427843 antibody, AU015727 antibody, AU015859 antibody, Socs7 antibody, SOCS6 antibody, socs7 antibody, socs4a antibody, suppressor of cytokine signaling 4 antibody, SOCS4 antibody, socs4 antibody, Socs4 antibody
    背景
    SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
    UniProt
    Q8WXH5
    途径
    JAK/STAT Signaling, EGFR Signaling Pathway
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