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SMAD4 抗体

SMAD4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal IMD-89 unconjugated
产品编号 ABIN1109062
发货至: 中国
  • 抗原 See all SMAD4 抗体
    SMAD4 (SMAD Family Member 4 (SMAD4))
    适用
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    宿主
    • 90
    • 11
    • 1
    小鼠
    克隆类型
    • 76
    • 26
    单克隆
    标记
    • 58
    • 9
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    This SMAD4 antibody is un-conjugated
    应用范围
    • 67
    • 46
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    • 9
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody reacts to SMAD4.
    纯化方法
    Affinity chromatography
    免疫原
    Recombinant human Smad4 (DPC4).
    克隆位点
    IMD-89
    亚型
    IgG1
    Top Product
    Discover our top product SMAD4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.2 % sodium acetate or neutral PBS
    浓度
    0,1 mg/mL
    缓冲液
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SMAD4 (SMAD Family Member 4 (SMAD4))
    别名
    SMAD4 (SMAD4 产品)
    别名
    smad4 antibody, DPC4 antibody, JIP antibody, MADH4 antibody, MYHRS antibody, AW743858 antibody, D18Wsu70e antibody, Madh4 antibody, XSmad4alpha antibody, Xsmad4 antibody, dpc4 antibody, jip antibody, madh4 antibody, xsmad4a antibody, SMAD family member 4 antibody, Smad4 protein antibody, SMAD family member 4, gene 1 L homeolog antibody, SMAD4 antibody, smad4 antibody, Smad4 antibody, smad4.1.L antibody
    背景
    SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4
    基因ID
    4089
    NCBI登录号
    NP_005350
    UniProt
    Q13485
    途径
    Cell Division Cycle, Chromatin Binding, Autophagy
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