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ROCK2 抗体 (N-Term)

ROCK2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1108892
发货至: 中国
  • 抗原 See all ROCK2 抗体
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    抗原表位
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    N-Term
    适用
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    人, 小鼠, 大鼠
    宿主
    • 98
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    克隆类型
    • 96
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    多克隆
    标记
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    This ROCK2 antibody is un-conjugated
    应用范围
    • 74
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects ROCK2 (N-term).
    交叉反应 (详细)
    Species reactivity (expected):MouseSpecies reactivity (tested):Human, rat
    纯化方法
    Immunogen affinity purified
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminal of human ROCK2 .Remarks: Sequence is identical to the related rat and mouse sequence.
    亚型
    IgG
    Top Product
    Discover our top product ROCK2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the lyophilized product at -20 °C. Following reconstitution, the antibody can be stores at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))
    别名
    ROCK2 (ROCK2 产品)
    别名
    rocka-a antibody, xROK antibody, rock2 antibody, rok2 antibody, ROCK2 antibody, B230113H15Rik antibody, ROKalpha antibody, Rho-kinase antibody, Rock-II antibody, Rock2m antibody, mKIAA0619 antibody, ROCK-II antibody, ROK antibody, Rho-associated, coiled-coil containing protein kinase 2 L homeolog antibody, rho-associated, coiled-coil containing protein kinase 2a antibody, Rho associated coiled-coil containing protein kinase 2 antibody, Rho-associated, coiled-coil containing protein kinase 2 antibody, Rho-associated coiled-coil containing protein kinase 2 antibody, rock2.L antibody, rock2a antibody, ROCK2 antibody, Rock2 antibody
    背景
    Rho-associated kinase (ROCK), including the ROCK-I and ROCK-II isoforms, is a protein kinase involved in signaling from Rho to actin cytoskeleton. Serine/threonine kinase ROCK II/Rho kinase, which is an isozyme of ROCK I, is one of the targets for the small GTPase Rho. ROCK II regulates the formation of actin stress fibers and focal adhesions, cytokinesis, smooth muscle contraction, and the activation of c-fos serum response element. Sequencing analysis has shown that human ROCK II contains 1388 amino acid residues with a calculated molecular mass of approximately 161 kDa. Fluorescence in situ hybridization analysis showed that the human ROCK II gene is located on chromosome 2p24.1 Thumkeo et al. (2003) concluded that ROCK-II is essential in inhibiting blood coagulation and maintaining blood flow in the endothelium-free labyrinth layer and that loss of ROCK-II leads to thrombus formation, placental dysfunction, intrauterine growth retardation, and fetal death.2Synonyms: KIAA0619, ROCK-2, Rho kinase 2, Rho-associated, Rho-associated protein kinase 2, coiled-coil-containing protein kinase 2, p164ROCK-2
    基因ID
    9475
    NCBI登录号
    NP_004841
    UniProt
    O75116
    途径
    Microtubule Dynamics, WNT signaling, Tube Formation
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