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LCK 抗体 (Internal Region)

Name: LCK 抗体 (Internal Region)
SKU: ABIN1108030
Availability: OutOfStock

LCK 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated

AP31924PU-N LCK antibody staining of Human Thymus lysate at 0. (LCK 抗体 (Internal Region))

1 image

产品编号 ABIN1108030

发货至: 中国

Datasheet as PDF

抗原 See all LCK 抗体

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
抗原表位
22

16

15

10

10

8

8

8

6

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 39-52, Internal Region
适用
158

92

58

7

6

4

4

4

4

3

3

2

1
人
宿主
142

14

2
山羊
Compatible Secondaries
克隆类型
144

15
多克隆
标记
90

10

9

7

5

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This LCK antibody is un-conjugated
应用范围
123

86

26

24

22

16

15

14

13

8

3

3

2

1

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

序列

C-RNGSEVRDPL VTYE

特异性

This antibody is not expected to cross-react with other Tyrosine protein kinases. Reported variants represent identical protein: NP_005347.3, NP_001036236.1

交叉反应（详细）

Species reactivity (tested):Human.

纯化方法

Affinity Chromatography

免疫原

Peptide with sequence from the internal region (near N-Terminus) of the protein sequence according to NP_005347.3. Genename: LCK

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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibody
LCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-100) antibody
LCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

别名

LCK (LCK 产品)

别名

zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody

背景

Lck (lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56 kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and non-lymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection.Synonyms: LSK, Lymphocyte cell-specific protein-tyrosine kinase, Proto-oncogene tyrosine-protein kinase LCK, T cell-specific protein-tyrosine kinase, p56-LCK

分子量

58.0 kDa (NP_005347.3).

基因ID

3932

NCBI登录号

NP_001036236

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling