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LBP 抗体

LBP 适用: 小鼠 WB, Func, EIA 宿主: 大鼠 Monoclonal M330-19 unconjugated
产品编号 ABIN1108025
发货至: 中国
  • 抗原 See all LBP 抗体
    LBP (Lipopolysaccharide Binding Protein (LBP))
    适用
    • 39
    • 19
    • 17
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    小鼠
    宿主
    • 45
    • 19
    • 4
    • 2
    大鼠
    克隆类型
    • 47
    • 23
    单克隆
    标记
    • 56
    • 7
    • 3
    • 3
    • 1
    This LBP antibody is un-conjugated
    应用范围
    • 46
    • 28
    • 24
    • 17
    • 9
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Mouse
    纯化方法
    Protein G
    克隆位点
    M330-19
    亚型
    IgG2a
    Top Product
    Discover our top product LBP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    LBP (Lipopolysaccharide Binding Protein (LBP))
    别名
    LBP (LBP 产品)
    别名
    BPIFD2 antibody, Bpifd2 antibody, Ly88 antibody, LPSBP antibody, LBP antibody, lipopolysaccharide binding protein antibody, lipopolysaccharide-binding protein antibody, LBP antibody, Lbp antibody, LOC100472839 antibody
    背景
    LPS binding protein (LBP) is an approximately 60 kDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on mononuclear phagocytes, leading to an 100-1,000-fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negative cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these cells. Next, LBP transfers LPS into High Density Lipoprotein (HDL), which effectively neutralizes its biological potency. LBP was demonstrated to protect mice from septic shock caused by LPS or gram negative bacteria.Synonyms: Lipopolysaccharide-binding protein
    基因ID
    10090
    UniProt
    Q61805
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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