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IL12A 抗体

IL12A 适用: 人 EIA 宿主: 小鼠 Monoclonal B-S35 unconjugated
产品编号 ABIN1107846
发货至: 中国
  • 抗原 See all IL12A 抗体
    IL12A (Interleukin 12 alpha (IL12A))
    适用
    • 57
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    宿主
    • 51
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    小鼠
    克隆类型
    • 57
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    单克隆
    标记
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    This IL12A antibody is un-conjugated
    应用范围
    • 56
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    Enzyme Immunoassay (EIA)
    特异性
    Recognises both natural and recombinant protein (no cross reaction with IL-12 and IL-27).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ion Exchange Chromatography
    免疫原
    EBI3 recombinant protein and IL-35/Fc recombinant protein. Myeloma X63/AG.8653 x Balb/c node cells.
    克隆位点
    B-S35
    亚型
    IgG1
    Top Product
    Discover our top product IL12A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS without carriers and preservatives
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    IL12A (Interleukin 12 alpha (IL12A))
    别名
    Interleukin-12 alpha / IL12A (IL12A 产品)
    别名
    CLMF antibody, IL-12A antibody, NFSK antibody, NKSF1 antibody, P35 antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p35 antibody, Il-12 p35 antibody, IL12p40 antibody, IL12 antibody, IL-12 p35 antibody, interleukin 12A antibody, interleukin 12B antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12A antibody, IL12B antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
    背景
    IL-35 or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to play an essential role in immune regulation of the CD4+CD25+ regulatory T (Treg) cells, from which IL-35 is also specifically produced. IL-35 is able to expand CD4+CD25+ Treg cells whereas it can inhibit proliferation of CD4+CD25- effector T (Teff) cells and development of proinflammatory Th17 cells, suppressing inflammatory responses.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
    基因ID
    3592
    NCBI登录号
    NP_000873
    UniProt
    P29459
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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