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IL12A 抗体 (AA 23-215)

There is 1 publication for this product available. The 兔 多克隆 anti-IL12A antibody is suitable to detect IL12A in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN5693302
发货至: 中国
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Quick Overview for IL12A 抗体 (AA 23-215) (ABIN5693302)

抗原

See all IL12A 抗体
IL12A (Interleukin 12 alpha (IL12A))

适用

  • 75
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  • 1
人, 小鼠, 大鼠

宿主

  • 62
  • 22
  • 5
  • 2
  • 2

克隆类型

  • 69
  • 24
多克隆

标记

  • 49
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  • 1
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This IL12A antibody is un-conjugated

应用范围

  • 61
  • 39
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  • 14
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  • 12
  • 7
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  • 4
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 14
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
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    AA 23-215

    原理

    Anti-IL12A Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL12A Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived rat IL12A recombinant protein (Position: R23-S215).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL ELISA, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • He, Liang, Guo, Huang, Niu, Dong, Wang, Zhang: "Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." in: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).

  • 抗原

    IL12A (Interleukin 12 alpha (IL12A))

    别名

    Il12a

    背景

    Background: Interleukin-12 subunit alpha (IL-12 p35) is a protein that in humans is encoded by the IL12A gene. This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

    Gene Full Name: interleukin 12A

    分子量

    35 kDa

    基因ID

    84405

    UniProt

    Q9R103

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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