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- 抗原 See all POLI 抗体
- POLI (Polymerase (DNA Directed) iota (POLI))
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抗原表位
- Middle Region, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLI antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PVVERLGFDE NFVDLTEMVE KRLQQLQSDE LSAVTVSGHV YNNQSINLLD
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - 纯化方法
- Immunoaffinity column
- 免疫原
- Synthetic peptide directed towards the N-terminal to middle region of human POLI
- Top Product
- Discover our top product POLI Primary Antibody
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anti-Polymerase (DNA Directed) iota (POLI) (AA 616-715) antibody
POLI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G9 unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 458-711) antibodyPOLI 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 458-740) antibodyPOLI 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B9 unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 50-350) antibodyPOLI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 51-150) antibodyPOLI 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (C-Term) antibodyPOLI 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 143-192) antibodyPOLI 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- 抗原
- POLI (Polymerase (DNA Directed) iota (POLI))
- 别名
- DNA Polymerase iota (POLI 产品)
- 别名
- poli antibody, wu:fc27h11 antibody, zgc:110185 antibody, GB12093 antibody, NV16187 antibody, RAD30B antibody, RAD3OB antibody, Rad30b antibody, DNA polymerase iota antibody, polymerase (DNA directed) iota antibody, polymerase (DNA directed), iota antibody, POLI antibody, poli antibody, LOC551219 antibody, AFUA_4G11140 antibody, LOC5568276 antibody, Pol-iota antibody, Poli antibody
- 背景
- DNA polymerase iota (POLI) is an error-prone DNA polymerase specifically involved in DNA repair. POLI plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. POLI favors Hoogsteen base-pairing in the active site. POLI inserts the correct base with high-fidelity opposite an adenosine template.POLI exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. POLI may play a role in hypermutation of immunogobulin genes. POLI forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.Synonyms: Eta2, POLI, RAD30 homolog B, RAD30B
- 分子量
- POLI: 83 kDa
- 基因ID
- 11201
- NCBI登录号
- NM_007195
- 途径
- DNA Damage Repair
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