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C5 抗体

C5 适用: 人 WB, IHC (p), IHC (fro), EIA, Func 宿主: 小鼠 Monoclonal 2952 unconjugated
产品编号 ABIN1106791
发货至: 中国
  • 抗原 See all C5 抗体
    C5 (Complement Component 5 (C5))
    适用
    • 124
    • 32
    • 19
    • 16
    • 2
    • 2
    • 2
    宿主
    • 113
    • 15
    • 6
    • 4
    小鼠
    克隆类型
    • 123
    • 14
    单克隆
    标记
    • 49
    • 13
    • 12
    • 9
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    This C5 antibody is un-conjugated
    应用范围
    • 69
    • 50
    • 42
    • 39
    • 26
    • 20
    • 12
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    2952
    亚型
    IgG1
    Top Product
    Discover our top product C5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.1 % bovine serum albumin
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    C5 (Complement Component 5 (C5))
    别名
    Complement C5 (C5 产品)
    别名
    C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
    背景
    C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5. C5a induces smooth muscle contraction, increases vascular permeability, causes degranulation of mast cells and basophils, and release of lysosomal enzymes. In addition C5a stimulates the directed migration of neutrophils, eosinophils, basophils and monocytes. Recent studies indicate the modulation of the acute-phase response in liver and an overall immune response by inducing synthesis of cytokines such as TNF-alpha IL-1beta, IL-6 and IL-8.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5
    基因ID
    9606
    UniProt
    P01031
    途径
    Complement System, Carbohydrate Homeostasis
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