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FLIP 抗体 (C-Term, long form)
CFLAR
适用: 人, 小鼠, 大鼠
WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
FLIP抗体详情
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抗原
See all FLIP (CFLAR) 抗体
FLIP (CFLAR)
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
抗原表位
All epitopes for FLIP 抗体
C-Term, long form
适用
All reactivities for FLIP 抗体
人, 小鼠, 大鼠
宿主
All hosts for FLIP 抗体
兔
克隆类型
All clonalities for FLIP 抗体
多克隆
标记
All conjugates for FLIP 抗体
This FLIP antibody is un-conjugated
应用范围
All applications for FLIP 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
Recognizes FLIP-L No cross reactivity with other proteins.
纯化方法
Immunoaffinity Chromatography
免疫原
A synthetic peptide corresponding to a sequence mapping at the C-terminal of Human FLIP- L, identical to the related Mouse sequence.
亚型
IgG
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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溶解方式
Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
浓度
0.5 mg/mL
缓冲液
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
储存液
Sodium azide, Thimerosal (Merthiolate)
注意事项
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
FLIP目标详情
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抗原
FLIP (CFLAR)
(CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
别名
CFLAR / Casper / I-FLICE (CFLAR 产品 )
别名
Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
背景
Irmler et al. (1997) isolated human cDNAs encoding 2 isoforms of FLIP. FLIP(L), the longer isoform, contains 2 DEDs and a caspase-like domain, and FLIP(S), the shorter isoform, contains only the 2 DEDs followed by a C-terminal extension of approximately 50 amino acids. High levels of FLIP(L) protein were detected in melanoma cell lines and malignant melanoma tumors. FLIP may be implicated in tissue homeostasis as an important regulator of apoptosis.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
基因ID
8837
NCBI登录号
NP_001120655
UniProt
O15519
途径
Apoptosis , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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