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TLR2 抗体

TLR2 适用: 小鼠 IP, IHC (fro), EIA 宿主: 小鼠 Monoclonal mTL2-7 unconjugated
产品编号 ABIN7101942
发货至: 中国
  • 抗原 See all TLR2 抗体
    TLR2 (Toll-Like Receptor 2 (TLR2))
    适用
    • 16
    • 6
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 14
    • 7
    小鼠
    克隆类型
    • 14
    • 7
    单克隆
    标记
    • 16
    • 2
    • 2
    • 1
    This TLR2 antibody is un-conjugated
    应用范围
    • 11
    • 11
    • 8
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    Monoclonal antibody mT2.7 reacts with mouse Toll-like receptor 2 (TLR2). The monoclonal antibody mT2.7 stained overexpressed, as well as endogenous cell surface- and intercellular TLR2. The antibody does not affect cell activation through TLR2.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Purified
    克隆位点
    MTL2-7
    亚型
    IgG2a
    Top Product
    Discover our top product TLR2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0,1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0,1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    TLR2 (Toll-Like Receptor 2 (TLR2))
    别名
    CD282 / TLR2 (TLR2 产品)
    别名
    CD282 antibody, TIL4 antibody, Ly105 antibody, toll like receptor 2 antibody, toll-like receptor 2 antibody, TLR2 antibody, Tlr2 antibody, tlr2 antibody
    背景
    Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. TLR2 has been identified as a receptor that is central to the innate immune response to lipoproteins of Gram-negative bacteria, several whole Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products. A functional interaction between TLR2 and TLR6 in the cellular response to various bacterial products has been discovered. The currently accepted paradigm regards TLR2 as an essential receptor for many eubacterial cell wall components, including lipoproteins and peptidoglycan. Bacterial species as diverse as mycobacteria, spirochetes, mycoplasma, Staphylococcus aureus, and Streptococcus pneumoniae have all been shown to mediate cellular activation via TLR2.Synonyms: Toll-like receptor 2
    基因ID
    9606
    UniProt
    O60603
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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